Project Description

Enabling neuronal celltype-specific tools and therapies

EDGE is a novel non-invasive, low risk, therapeutic approach that enables brain region/neuron cell-specific interventions. Taking advantage of region-specific enhancers to construct viral vectors, the technology can target the particular cells involved in neuronal diseases such as Parkinson and Alzheimer disease. EDGE is the first ever tool to enable delivery of therapeutic gene-loads into specific regions of the brain.